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US Study: Multiple Sclerosis Drug Found to Accelerate Bone Healing

Doha: A new study by researchers at the University of Arizona revealed that a drug commonly used to treat multiple sclerosis may play a key role in accelerating bone healing. The researchers found that 4-aminopyridine (4-AP), prescribed to improve walking ability in patients with neurological disorders, also speeds up bone recovery. According to Qatar News Agency, in laboratory experiments, mice with fractures that received the drug healed faster, developed stronger bones, and produced more bone tissue compared to those that did not. The scientists also observed that the drug stimulates production of BMP2 protein, which drives the formation of new bone cells (osteoblasts), enhances bone mineralization, and boosts collagen production, strengthening bones and improving their resistance to stress. To test its impact on human cells, the team treated stem cells with 4-AP, which quickly transformed into bone-forming cells. These were then used to accelerate fracture healing in patients. The researchers described the drug as a breakthrough in fracture treatment, noting that it opens new horizons in bone repair protocols, especially since the drug is already clinically approved and widely tested, which could ease its integration into future medical applications. Bones form the body's skeletal framework, supporting posture, protecting internal organs, storing minerals, producing blood cells, and enabling movement through their connections with muscles and joints. Bone tissue is continuously renewed throughout life.